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Basics of memory B‐cell responses: lessons from and for the real …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328991/
webNov 29, 2018 · Memory B cells established after primary and secondary infections appear to retain a greater breadth of antigen specificities (E, prM, and complex epitopes) than do the responding plasmablasts (predominately E). 51, 52 Hence, only a subset of memory B cells differentiates into antibody‐secreting cells, where the majority of antibodies are ...
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Memory B cell - Wikipedia
https://en.wikipedia.org/wiki/Memory_B_cell
webIn immunology, a memory B cell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells develop within germinal centers of the secondary lymphoid organs. Memory B cells circulate in the blood stream in a quiescent state, sometimes for decades.
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Memory B cells | Nature Reviews Immunology
https://www.nature.com/articles/s41577-023-00897-3
webJul 3, 2023 · Here, we review the cellular and molecular mechanisms by which memory B cells are generated and how these processes shape the antibody diversity and breadth of memory B cells.
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Understanding and making use of human memory B cells - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165660/
webJun 13, 2006 · Human memory and naive B cells can be identified using a combination of markers that include immunoglobulin (Ig) isotypes, CD27, which is expressed on most memory B cells ( 5 ), and ABCB1, a multidrug transporter molecule that precisely discriminates naive from memory and transitional B cells ( 6 ).
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Human B cell memory - PMC - National Center for Biotechnology Information
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134627/
webJun 8, 2009 · Following an immune response two types of differentiated B cells persist in the memory pool: plasma cells, which confer immediate protection by the secretion of specific antibodies; and memory B cells, which confer rapid …
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Memory B cells | Nature Reviews Immunology
https://www.nature.com/articles/nri3802
webFeb 13, 2015 · Nature Reviews Immunology - New insights into the heterogeneity of memory B cells can aid our mechanistic understanding of the longevity of humoral memory and its rapid and robust...
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B cell memory: building two walls of protection against pathogens - Nature
https://www.nature.com/articles/s41577-019-0244-2
webDec 13, 2019 · This study reveals that memory B cells and long-lived plasma cells are produced in different phases of the GC reaction, with memory B cell formation preceding the formation of plasma...
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Memory B-Cell | Ask A Biologist
https://askabiologist.asu.edu/memory-b-cell
webAug 4, 2011 · With the help of Memory B-cells, the second time your body sees that virus, it can do the same in thing 5 days. It also makes 100 times more antibodies than it did the first time. The faster your body makes antibodies, the quicker the virus can be destroyed.
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Memory B cells - PubMed
https://pubmed.ncbi.nlm.nih.gov/37400644/
webHere, we review the cellular and molecular mechanisms by which memory B cells are generated and how these processes shape the antibody diversity and breadth of memory B cells. Then, we discuss the mechanisms of memory B cell reactivation in the context of established immune memory; the contribution of antibody feedback to this process has …
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Memory B Cell - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/immunology-and-microbiology/memory-b-cell
webB cell memory is generated upon a first pathogen encounter and is carried by two distinct lineages: long-lived plasma cells that secrete protective antibodies for a lifetime and memory B cells that can elicit improved and enhanced …
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