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Human memory T cells: generation, compartmentalization and …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032067/
WebMemory T cell frequency, pathogen susceptibility and mortality throughout human life. Memory T cells pass through three distinct phases: memory generation, memory homeostasis and immunosenescence. Memory T cells are mostly generated following antigen exposure during infancy, youth and young adulthood (ages 0–20).
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Memory T cell - Wikipedia
https://en.wikipedia.org/wiki/Memory_T_cell
WebClones of memory T cells expressing a specific T cell receptor can persist for decades in our body. Since memory T cells have shorter half-lives than naïve T cells do, continuous replication and replacement of old cells are likely involved in the maintenance process.
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Human memory T cells: generation, compartmentalization and
https://www.nature.com/articles/nri3567
WebDec 13, 2013 · In this Review, we discuss studies focused on human memory T cells that reveal key properties of these cells, including subset heterogeneity and diverse tissue residence in multiple mucosal...
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CD8+ T-Cell Memory: The Why, the When, and the How - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091951/
WebVirtual memory T cells (Tvm cells), otherwise known as memory phenotype (MP) cells, are a population of antigenically naive CD8 + T cells that comprise ∼5%–15% of total circulating CD8 + T cells and express markers of conventional memory T cells (e.g., high levels of CD44 and CD122).
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The origins of memory T cells - Nature
https://www.nature.com/articles/d41586-017-08280-8
WebDec 13, 2017 · Memory T cells protect against previously encountered pathogens, but their origins are unclear. Two studies track DNA modifications over time and find that these cells arise from effector T...
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Two parallel worlds of memory T cells | Nature Immunology
https://www.nature.com/articles/s41590-020-00815-y
WebOct 12, 2020 · In contrast with the classical dogma that the pathways generating either memory or ‘exhausted’ T cells are strictly segregated, data now identify a clonally distinct hybrid memory T...
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T Cell Memory: Understanding COVID-19 - PMC - National …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749639/
WebJan 1, 2021 · Hallmarks of memory T cell responses include (1) an increased pool of memory T cells reactive to the pathogen through specific recognition of pathogen-derived antigens by the TCR, (2) a more rapid and powerful response to infection, (3) preprogramming to generate a “tailored” set of effector cell types optimized to fight the …
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Memory T Cell - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/immunology-and-microbiology/memory-t-cell
WebMemory T cells are antigen-specific T cells that remain long-term after an infection has been eliminated. The memory T cells are quickly converted into large numbers of effector T cells upon reexposure to the specific invading antigen, thus providing a …
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T-Cells: Types and Function - Cleveland Clinic
https://my.clevelandclinic.org/health/body/24630-t-cells
WebSome of your T-cells become memory cells instead of effector cells. Unlike effector T-cells, memory T-cells aren’t fighters. Instead, they remember the intruder so that if it returns, your immune system recognizes it and quickly mounts a defense.
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The evolving role of tissue-resident memory T cells in ... - Science
https://www.science.org/doi/10.1126/sciadv.abo5871
WebAug 17, 2022 · Resident memory T cells (T RM) form a distinct type of T memory cells that stably resides in tissues. T RM form an integral part of the immune sensing network and have the ability to control local immune homeostasis and participate in immune responses mediated by pathogens, cancer, and possibly autoantigens during autoimmunity.
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