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Nicotinamide adenine dinucleotide phosphate - Wikipedia
https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide_phosphate
WEBNicotinamide adenine dinucleotide phosphate, abbreviated NADP + or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').
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NADPH - Definition and Function | Biology Dictionary
https://biologydictionary.net/nadph/
WEBApr 28, 2017 · NADPH Definition. NADPH is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. Typically enzymes involved in anabolic pathways that create large molecules use NADPH, while enzymes involved in the breakdown of molecules use the analog NADH.
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NADPH homeostasis in cancer: functions, mechanisms and
https://www.nature.com/articles/s41392-020-00326-0
WEBOct 7, 2020 · Nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron donor in all organisms, and provides the reducing power for anabolic reactions and redox balance. NADPH...
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The light-dependent reactions - Khan Academy
https://www.khanacademy.org/science/ap-biology/cellular-energetics/photosynthesis/a/light-dependent-reactions
WEBThe light-dependent reactions use light energy to make two molecules needed for the next stage of photosynthesis: the energy storage molecule ATP and the reduced electron carrier NADPH. In plants, the light reactions take place in the thylakoid membranes of organelles called chloroplasts.
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Nicotinamide adenine dinucleotide - Wikipedia
https://en.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide
WEBIn contrast, the main function of NADPH is as a reducing agent in anabolism, with this coenzyme being involved in pathways such as fatty acid synthesis and photosynthesis. Since NADPH is needed to drive redox reactions as a strong reducing agent, the NADP + /NADPH ratio is kept very low.
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NAD(H) and NADP(H) Redox Couples and Cellular Energy …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737637/
WEBJan 1, 2018 · The level of cellular NAD (H)/NADP (H) is essential for maintaining redox homeostasis. Deficiency in these redox couples can lead to oxidative or reductive stress, depending on the redox ratio of each. Both oxidative stress and reductive stress are detrimental to normal cell functions.
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NADPH—The Forgotten Reducing Equivalent - PMC - National …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168431/
WEBNADPH is the major reducing equivalent driving de novo synthesis of fatty acids, cholesterol, amino acids, and nucleotides. Its other major function is generation of superoxide (O 2−) by NADPH oxidases (NOXs) and scavenging of H 2 O 2 by regenerating GSH and the antioxidant protein thioredoxin (TRX).
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NADPH production by the oxidative pentose-phosphate pathway …
https://www.nature.com/articles/s42255-019-0043-x
WEBMar 11, 2019 · NADPH donates high-energy electrons for antioxidant defence and reductive biosynthesis. Cytosolic NADP is recycled to NADPH by the oxidative pentose-phosphate pathway (oxPPP), malic enzyme 1...
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NADPH levels affect cellular epigenetic state by inhibiting ... - Nature
https://www.nature.com/articles/s42255-020-00330-2
WEBJan 18, 2021 · NADPH is a key component in cellular anti-oxidation systems and an indispensable electron donor in numerous enzymatic reactions and biosynthetic reactions, such as nucleotide synthesis, lipid...
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NADPH | C21H30N7O17P3 | CID 5884 - PubChem
https://pubchem.ncbi.nlm.nih.gov/compound/NADPH
WEBNADPH is the reduced form of NADP+; used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. It has a role as a fundamental metabolite and a cofactor. It is a NAD(P)H and a NADP. …
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