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NADPH oxidase - Wikipedia
https://en.wikipedia.org/wiki/NADPH_oxidase
WEBNADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found in the plasma membrane as well as in the membranes of phagosomes used by neutrophil white blood cells to engulf microorganisms.
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NADPH Oxidases (NOX): An Overview from Discovery, Molecular …
https://pubmed.ncbi.nlm.nih.gov/34205998/
WEBJun 1, 2021 · Abstract. The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first identified in the membrane of phagocytic cells. For many years, its only known role was in immune defense, where its ROS production leads to the destruction of pathogens by the immune cells. NOX from phagocytes catalyzes, via one-electron …
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NADPH oxidases: an overview from structure to innate immunity
https://www.nature.com/articles/cmi201489
WEBSep 29, 2014 · NADPH oxidase is a multisubunit enzyme comprising membrane and cytosolic components, which actively communicate during the host responses to a wide variety of stimuli, including viral and...
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NADPH Oxidases (NOX): An Overview from Discovery, Molecular …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228183/
WEBJun 1, 2021 · The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first identified in the membrane of phagocytic cells. For many years, its only known role was in immune defense, where its ROS production leads to the destruction of pathogens by the immune cells.
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NADPH oxidases: an overview from structure to innate immunity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654378/
WEBSep 29, 2014 · NADPH oxidase is a multisubunit enzyme comprising membrane and cytosolic components, which actively communicate during the host responses to a wide variety of stimuli, including viral and bacterial infections.
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NADPH Oxidase Deficiency: A Multisystem Approach - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753020/
WEBDec 21, 2017 · NADPH oxidase (NOX) plays a pivotal role in the production of ROS, and the defect of its different subunits leads to the development of chronic granulomatous disease (CGD). The defect of the different NOX subunits in CGD affects different organs.
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NADPH Oxidases: Structure and Function - Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1002/9781118355886.ch7
WEBJun 28, 2013 · Summary. This chapter describes the key structural and functional features of the phagocyte and nonphagocyte NADPH oxidases. It discusses their roles in physiological and pathophysiological events. The NADPH oxidases are a family of multi-subunit enzymes that catalyze the formation of reactive oxygen species (ROS).
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NADPH Oxidase | SpringerLink
https://link.springer.com/referenceworkentry/10.1007/978-3-030-57401-7_10023
WEBFirst Online: 01 January 2022. Download reference work entry PDF. Synonyms. NAD (P)H oxidase; NAD (P)H:oxygen oxidoreductase. Definition. NADPH (nicotinamide adenine dinucleotide phosphate) oxidase (EC 1.6.3.1) is an enzyme that produces superoxide anions by transferring electrons from reduced NADPH (the electron donor) to …
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NADPH Oxidase - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/neuroscience/nadph-oxidase
WEBNADPH oxidase is a flavocytochrome b heterodimer that consists of two protein subunits, p22‐phox and either p91‐phox in fibroblasts or Nox1 in smooth muscle cells. NAD/NADPH oxidase is membrane bound and is the most powerful source of …
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NADPH oxidases: Current aspects and tools - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S2213231720301208
WEBJul 1, 2020 · NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with intracellular signaling cascades without disturbing the signaling itself. Many tools have been developed to study or inhibit the functions and roles of the NADPH …
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