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Prostaglandin E2 is essential for efficacious skeletal muscle
http://go.microsoft.com/fwlink/?LinkID=617350
WEBHere we show that Prostaglandin E2 (PGE2) is an inflammatory cytokine that directly targets MuSCs via the EP4 receptor, leading to MuSC expansion. An acute treatment with PGE2 suffices to robustly augment muscle regeneration by either endogenous or transplanted MuSCs.
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