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Chronic Granulomatous Disease - Immunology
https://step1.medbullets.com/immunology/105009/chronic-granulomatous-disease
WebNov 30, 2020 · results in deficiency in NADPH oxidase. Epidemiology. males > females due to inheritance pattern. Pathogenesis. recall normal physiology. NADPH oxidase is important in respiratory or oxidative …
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Chronic granulomatous disease - Wikipedia
https://en.wikipedia.org/wiki/Chronic_granulomatous_disease
OverviewPathophysiologySymptoms and signsGeneticsDiagnosisTreatmentPrognosisEpidemiologyPhagocytes (i.e. neutrophils and macrophages) require an enzyme to produce reactive oxygen species to destroy bacteria after they are ingested (phagocytosis), a process known as the respiratory burst. This enzyme is termed "phagocyte NADPH oxidase" (PHOX). This enzyme oxidizes NADPH and reduces molecular oxygen to produce superoxide anions, a reactive oxygen species. Su… Other names: Bridges–Good syndrome, chronic granulomatous disorder, Quie syndrome
Other names: Bridges–Good syndrome, chronic granulomatous disorder, Quie syndrome
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Chronic Granulomatous Disease of Childhood (CGD)
https://step2.medbullets.com/pediatrics/120736/chronic-granulomatous-disease-of-childhood-cgd
WebDec 25, 2021 · Introduction. Chronic granulomatous disease (CGD) is a rare primary immunodeficiency of phagocytes. Epidemiology. Males > females due to inheritance pattern. etiology. Pathogenesis. recall normal …
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Chronic granulomatous disease: Pathogenesis, clinical …
https://www.uptodate.com/contents/chronic-granulomatous-disease-pathogenesis-clinical-manifestations-and-diagnosis
WebOct 26, 2023 · CGD is caused by defects in the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex, which constitutes the phagocyte …
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NADPH Oxidase Deficiency: A Multisystem Approach
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753020/
WebDec 21, 2017 · Autoinflammatory and autoimmune disorders have been identified in patients with CGD, female carriers for NOX2 deficiency, and patients carrying oxidase gene … Author: Giuliana Giardino, Maria Pia Cicalese, Ottavia Delmonte, Maddalena Migliavacca, Boaz Palterer, Loren... Publish Year: 2017
Author: Giuliana Giardino, Maria Pia Cicalese, Ottavia Delmonte, Maddalena Migliavacca, Boaz Palterer, Loren...
Publish Year: 2017
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Chronic Granulomatous Disease - StatPearls - NCBI …
https://www.ncbi.nlm.nih.gov/books/NBK493171/
WebDec 26, 2022 · Defective phagocyte NADPH oxidase causes the disease. The ultimate result is phagocytes' inability, such as neutrophils, monocytes, and macrophages, to destroy certain microbes. This article describes …
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Chronic granulomatous disease: Video & Anatomy | Osmosis
https://www.osmosis.org/learn/Chronic_granulomatous_disease
WebThe lysosomal enzymes also activate NADPH oxidase, which came from the phagosome, causing NADPH to undergo oxidation, and lose one of its electrons. Nearby oxygen …
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